Last updated: 2025 BLS data · Page refreshed:
The highest paying job in Mississippi is Orthopedic Surgeons, Except Pediatric, with a median salary of $544,130 per year. Below is the complete ranking of the top 25 careers in MS based on 2025 Bureau of Labor Statistics data.
Data: BLS Occupational Employment and Wage Statistics (OEWS), May 2025
See how Mississippi compares to other states. Click any state for its top-paying jobs.
Ranked by median annual salary. Click any job to see the full salary breakdown including percentile data and state-by-state comparisons.
| Rank | Occupation | Median Salary | Mean Salary | Workers |
|---|---|---|---|---|
| 1 | Orthopedic Surgeons, Except Pediatric | $544,130 | $523,450 | N/A |
| 2 | General Internal Medicine Physicians | $325,610 | $275,760 | 390 |
| 3 | Physicians, Pathologists | $261,570 | $273,380 | 50 |
| 4 | Emergency Medicine Physicians | $252,960 | $300,550 | 450 |
| 5 | Family Medicine Physicians | $235,630 | $265,510 | 570 |
| 6 | Psychiatrists | $213,680 | $218,620 | 110 |
| 7 | Nurse Anesthetists | $198,410 | $217,470 | 480 |
| 8 | Pediatricians, General | $183,650 | $214,380 | 40 |
| 9 | Podiatrists | $164,410 | $158,190 | 30 |
| 10 | Dentists, General | $143,660 | $149,300 | 740 |
| 11 | Airline Pilots, Copilots, and Flight Engineers | $143,580 | $151,890 | 360 |
| 12 | Architectural and Engineering Managers | $142,790 | $147,070 | 860 |
| 13 | Chief Executives | $139,250 | $173,720 | 310 |
| 14 | Health Specialties Teachers, Postsecondary | $137,220 | $166,400 | 1,890 |
| 15 | Pharmacists | $133,230 | $130,320 | 3,050 |
| 16 | Physicists | $129,970 | $137,740 | 80 |
| 17 | Nurse Practitioners | $124,730 | $125,340 | 4,690 |
| 18 | Computer and Information Systems Managers | $124,280 | $131,880 | 1,710 |
| 19 | Purchasing Managers | $122,940 | $122,820 | 320 |
| 20 | Natural Sciences Managers | $119,430 | $126,990 | 210 |
| 21 | Industrial Production Managers | $118,660 | $125,490 | 2,290 |
| 22 | Medical Dosimetrists | $115,490 | $110,850 | 40 |
| 23 | Electronics Engineers, Except Computer | $112,400 | $111,650 | 160 |
| 24 | Geoscientists, Except Hydrologists and Geographers | $112,400 | $115,470 | 250 |
| 25 | Financial Managers | $111,390 | $128,380 | 3,470 |
The top-paying careers in Mississippi are concentrated in Healthcare Practitioners fields. The #1 job, Orthopedic Surgeons, Except Pediatric, pays $482,647 more than the state average of $61,482 per year.
At the 90th percentile, experienced Orthopedic Surgeons, Except Pediatric professionals in MS can earn up to $621,270 annually — making it one of the most lucrative career paths in the state.
Among the top 25, the minimum median salary is $111,390, meaning all jobs on this list pay significantly above the national average.
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See how Mississippi's top salaries compare to other states.
Rankings are based on median annual salary from the U.S. Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics (OEWS) survey, May 2025 estimates. We use median rather than mean salary because it better represents typical earnings and is less affected by outliers.
Only occupations with state-level data published by BLS are included. Some specialized or rare occupations may not have data for every state. For full methodology details, see our Methodology page.