Last updated: 2025 BLS data · Page refreshed:
There are 81 occupations in South Carolina with a median salary above $100K per year. The highest-paying is General Internal Medicine Physicians at $359,500/year. Based on 2025 Bureau of Labor Statistics data.
Data: BLS Occupational Employment and Wage Statistics (OEWS), May 2025
Average salaries across all 50 states. Click a state to see its $100K+ jobs.
Ranked by median annual salary. Click any job to see the full salary breakdown.
| # | Occupation | Median Salary | Mean Salary | Workers |
|---|---|---|---|---|
| 1 | General Internal Medicine Physicians | $359,500 | $315,380 | 1,260 |
| 2 | Neurologists | $352,680 | $354,250 | 40 |
| 3 | Emergency Medicine Physicians | $341,960 | $285,730 | 80 |
| 4 | Orthodontists | $311,450 | $292,350 | N/A |
| 5 | Obstetricians and Gynecologists | $302,340 | $268,740 | 350 |
| 6 | Nurse Anesthetists | $265,480 | $276,380 | 1,010 |
| 7 | Dermatologists | $259,990 | $287,560 | 180 |
| 8 | Family Medicine Physicians | $239,200 | $244,960 | 1,200 |
| 9 | Anesthesiologists | $238,970 | $283,240 | 950 |
| 10 | Psychiatrists | $237,250 | $226,360 | 200 |
| 11 | Physicians, Pathologists | $236,950 | $278,740 | 80 |
| 12 | Pediatricians, General | $217,120 | $233,160 | 420 |
| 13 | Ophthalmologists, Except Pediatric | $214,160 | $275,240 | 100 |
| 14 | Radiologists | $174,480 | $232,030 | N/A |
| 15 | Architectural and Engineering Managers | $169,040 | $173,140 | 3,200 |
| 16 | Chief Executives | $168,840 | $211,720 | 1,740 |
| 17 | Podiatrists | $167,110 | $177,870 | 70 |
| 18 | Law Teachers, Postsecondary | $162,400 | $155,340 | 110 |
| 19 | Computer and Information Systems Managers | $160,860 | $166,190 | 4,930 |
| 20 | Dentists, General | $158,640 | $181,570 | 2,140 |
| 21 | Advertising and Promotions Managers | $156,300 | $156,030 | N/A |
| 22 | Optometrists | $145,950 | $129,570 | 480 |
| 23 | Airline Pilots, Copilots, and Flight Engineers | $143,580 | $150,970 | 110 |
| 24 | Marketing Managers | $143,290 | $162,650 | 3,760 |
| 25 | Medical Dosimetrists | $140,530 | $138,680 | 60 |
| 26 | Physicists | $138,400 | $159,280 | 420 |
| 27 | Aerospace Engineers | $137,030 | $131,390 | 650 |
| 28 | Marine Engineers and Naval Architects | $136,990 | $125,430 | 40 |
| 29 | Financial Managers | $136,160 | $160,800 | 9,020 |
| 30 | Pharmacists | $135,700 | $136,730 | 5,320 |
| 31 | Computer Network Architects | $134,990 | $136,370 | 1,950 |
| 32 | Purchasing Managers | $131,720 | $138,410 | 830 |
| 33 | Natural Sciences Managers | $131,140 | $143,720 | 780 |
| 34 | Sales Managers | $131,080 | $143,660 | 9,340 |
| 35 | Database Architects | $130,000 | $133,300 | 1,160 |
| 36 | Software Developers | $129,450 | $136,240 | 13,230 |
| 37 | Computer and Information Research Scientists | $126,980 | $122,950 | 430 |
| 38 | Industrial Production Managers | $126,880 | $136,170 | 6,390 |
| 39 | Nuclear Engineers | $126,570 | $125,440 | 1,440 |
| 40 | Computer Hardware Engineers | $125,110 | $124,320 | 690 |
| 41 | Administrative Services Managers | $124,320 | $135,880 | N/A |
| 42 | Human Resources Managers | $124,290 | $135,830 | 2,400 |
| 43 | Nurse Practitioners | $123,290 | $124,170 | 5,670 |
| 44 | Physician Assistants | $122,490 | $120,720 | 2,250 |
| 45 | Nurse Midwives | $122,390 | $120,550 | 100 |
| 46 | Veterinarians | $122,130 | $126,280 | 1,380 |
| 47 | Materials Engineers | $121,610 | $116,020 | 600 |
| 48 | Lawyers | $120,310 | $144,700 | 7,890 |
| 49 | Training and Development Managers | $119,460 | $128,760 | 610 |
| 50 | Nuclear Power Reactor Operators | $118,620 | $114,610 | 320 |
| 51 | Sales Engineers | $114,250 | $120,430 | 770 |
| 52 | Electronics Engineers, Except Computer | $113,720 | $117,570 | 1,030 |
| 53 | Air Traffic Controllers | $112,030 | $110,990 | 190 |
| 54 | Sales Representatives, Wholesale and Manufacturing, Technical and Scientific Products | $111,190 | $121,990 | 3,760 |
| 55 | Biochemists and Biophysicists | $109,080 | $110,710 | 60 |
| 56 | Economics Teachers, Postsecondary | $109,060 | $117,970 | 110 |
| 57 | Food Scientists and Technologists | $108,660 | $111,910 | 90 |
| 58 | Nuclear Technicians | $108,490 | $108,360 | 750 |
| 59 | Construction Managers | $108,110 | $123,420 | 5,620 |
| 60 | Transportation, Storage, and Distribution Managers | $106,860 | $121,290 | 3,460 |
| 61 | General and Operations Managers | $106,080 | $127,450 | 32,230 |
| 62 | Information Security Analysts | $105,800 | $115,090 | 1,720 |
| 63 | Commercial Pilots | $105,740 | $108,640 | 290 |
| 64 | Medical and Health Services Managers | $105,620 | $129,160 | 9,350 |
| 65 | Public Relations Managers | $104,920 | $125,350 | 650 |
| 66 | Mechanical Engineers | $104,580 | $113,690 | 5,780 |
| 67 | Health and Safety Engineers, Except Mining Safety Engineers and Inspectors | $104,120 | $108,210 | 280 |
| 68 | Facilities Managers | $103,940 | $113,950 | 1,750 |
| 69 | Engineering Teachers, Postsecondary | $103,420 | $120,010 | 490 |
| 70 | Fundraising Managers | $103,240 | $120,750 | 220 |
| 71 | Education Administrators, Kindergarten through Secondary | $102,440 | $105,080 | 5,000 |
| 72 | Materials Scientists | $101,930 | $105,730 | 80 |
| 73 | Civil Engineers | $101,600 | $107,000 | 7,180 |
| 74 | Chemical Engineers | $101,570 | $106,920 | 390 |
| 75 | Architects, Except Landscape and Naval | $101,550 | $103,670 | 1,030 |
| 76 | Physical Therapists | $101,330 | $98,100 | 3,930 |
| 77 | Occupational Therapists | $101,130 | $97,180 | 1,840 |
| 78 | Industrial Engineers | $101,060 | $104,740 | 7,960 |
| 79 | Radiation Therapists | $100,790 | $100,690 | 200 |
| 80 | Management Analysts | $100,660 | $112,690 | 12,340 |
| 81 | Social Work Teachers, Postsecondary | $100,400 | $101,920 | 80 |
The $100K+ jobs in South Carolina are concentrated in Healthcare Practitioners, Management fields.
12.3% of all tracked occupations in SC earn a median salary above $100K. The entry point for this group is $100,400/year (Social Work Teachers, Postsecondary), while the top earner makes $359,500/year.
South Carolina ranks #32 among all 50 states for the number of $100K+ jobs.
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These are gross salaries. After federal, state, and FICA taxes, take-home pay is lower.
This list includes all occupations with BLS-published state-level median salary data above $100K per year. Data from the U.S. Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics (OEWS), May 2025 estimates. See our Methodology page for details.