Last updated: 2025 BLS data · Page refreshed:
How much does a Physician Assistants actually take home in Mississippi?
Progressive (up to 4.7%) — 26.2% effective total tax rateData: BLS OEWS 2025 + IRS/State Tax Brackets 2024 • Updated 2026-05-19
Detailed line-by-line tax calculation for a Physician Assistants earning $105,920 in Mississippi (single filer, standard deduction).
| Tax Component | Annual Amount | Effective Rate |
|---|---|---|
| Gross Salary (Median) | $105,920 | — |
| Federal Income Tax | -$15,143 | 14.3% |
| Mississippi State Income Tax | -$4,508 | 4.3% |
| Social Security (OASDI) | -$6,567 | 6.2% |
| Medicare | -$1,535 | 1.4% |
| Total Taxes | -$27,754 | 26.2% |
| Take-Home Pay | $78,165 | 73.8% |
Take-home pay varies significantly across experience levels. Here is the after-tax breakdown for each salary percentile of Physician Assistants in Mississippi.
| Percentile | Gross Salary | Total Taxes | Take-Home Pay | Tax Rate |
|---|---|---|---|---|
| 10th Percentile (P10) | $44,030 | -$8,267 | $35,762 | 18.8% |
| 25th Percentile (P25) | $82,580 | -$19,737 | $62,842 | 23.9% |
| Median (P50) | $105,920 | -$27,754 | $78,165 | 26.2% |
| 75th Percentile (P75) | $132,680 | -$37,297 | $95,382 | 28.1% |
| 90th Percentile (P90) | $165,630 | -$49,275 | $116,355 | 29.8% |
After federal income tax ($15,143), state tax ($4,508), and FICA ($8,102), a Physician Assistants in Mississippi takes home $78,165 per year — or $6,513 per month. The effective tax rate of 26.2% is moderate compared to the national range.
A Physician Assistants in Mississippi loses 26.2% of gross pay to taxes — higher than the ~25% national midpoint. Of the $105,920 gross, $78,165 lands in the paycheck after federal ($15,143), state ($4,508), and FICA ($8,103) withholding.
Mississippi uses a progressive state income tax, so brackets escalate as wages rise. For this Physician Assistants salary the state tax works out to $4,508 (4.3% effective) — on top of federal and FICA.
Federal tax on this Physician Assistants salary is $15,143 (55%), but combined state ($4,508, 16%) + FICA ($8,103, 29%) make up the other 45% of the bill.
Moving this same Physician Assistants salary to a zero-state-tax state would yield around $82,674 net — a gain of $4,508 (5.8%) per year versus Mississippi.
Mississippi sits near the bottom (#50 of 51) for Physician Assistants after-tax earnings. Relocation, negotiation, or credential stacking typically show the clearest ROI in bottom-quartile states.
Translated into paycheck cadences, $78,165 net/year works out to $6,514/month or $3,006/bi-weekly for this Physician Assistants in Mississippi — the numbers that actually hit a checking account after every deduction.
Where does a Physician Assistants keep the most of their paycheck? Top 10 states ranked by after-tax take-home pay.
Mississippi ranks #50 out of 51 states for Physician Assistants after-tax take-home pay.
A Physician Assistants in Mississippi earning a median salary of $105,920 will take home approximately $78,165 per year after federal income tax ($15,143), state income tax ($4,508), and FICA ($8,102). That is $6,513 per month or $3,006 per bi-weekly paycheck.
The effective total tax rate for a Physician Assistants in Mississippi is 26.2%, broken down as: federal income tax 14.3%, Mississippi state tax 4.3%, and FICA (Social Security + Medicare) 7.6%. This assumes a single filer with the standard deduction for 2024.
Mississippi has a progressive (up to 4.7%). On a Physician Assistants's median salary of $105,920, the state income tax amounts to $4,508 per year, which is an effective state rate of 4.3%.
After all taxes, a Physician Assistants in Mississippi takes home approximately $6,513 per month, or about $37.58 per hour (based on a standard 2,080-hour work year). These figures assume a single filer, standard deduction, and no additional pre-tax deductions.
We start with the 2025 BLS median salary of $105,920 for Physician Assistants in Mississippi, then subtract: federal income tax using 2024 IRS brackets ($14,600 standard deduction), Mississippi state income tax (progressive (up to 4.7%)), Social Security (6.2% up to $168,600), and Medicare (1.45%). The result — $78,165/yr — does not include local taxes, pre-tax deductions (401k, HSA), or tax credits.
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This estimate assumes a single filer using the 2024 standard deduction ($14,600), with W-2 employment income only. It does not account for: itemized deductions, tax credits (e.g. earned income credit, child tax credit), local/city taxes, pre-tax contributions (401k, HSA, FSA), self-employment tax, or additional income sources. Actual take-home pay may differ. Consult a tax professional for personalized advice.
Our Methodology · Data Sources · Salary: BLS OEWS · Tax: IRS + State DOR