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Nurse Practitioners Salary in South Carolina: Cost of Living Adjusted (2025)

Last updated: 2025 BLS data · Page refreshed:

What does a Nurse Practitioners salary really buy you in South Carolina?

South Carolina is 6.4% cheaper than the US average

Data: BLS OEWS 2025 + BEA Regional Price Parities 2022 • Updated 2026-05-19

Nominal Salary
$123,290
Median annual (2025)
+6.8%
Real Purchasing Power
$131,720
COL-adjusted (RPP=93.6)

South Carolina Cost of Living Index

South Carolina's Regional Price Parity (RPP) is 93.6, meaning prices are 6.4% lower the national average. A Nurse Practitioners earning $123,290 in South Carolina has the equivalent purchasing power of $131,720 in an average-cost US state.

SC: 93.6
Cheapest (~85) US Avg (100) Priciest (~115)

Salary Breakdown: Nominal vs. COL-Adjusted

Every dollar goes further in low-cost states. Here is how each salary percentile compares after adjusting for South Carolina's cost of living.

Percentile Nominal Salary COL-Adjusted Difference
10th Percentile (P10) $97,080 $103,717 +$6,637
25th Percentile (P25) $107,930 $115,309 +$7,379
Median (P50) $123,290 $131,720 +$8,430
75th Percentile (P75) $132,220 $141,260 +$9,040
90th Percentile (P90) $160,170 $171,121 +$10,951
Key Insight

A Nurse Practitioners in South Carolina earns $123,290 on paper, but low living costs mean your money goes 7% further — like earning $131,720 in an average-cost state. This makes South Carolina one of the best value states for this occupation.

What the Cost-of-Living Data Says

South Carolina Sits Near the National Cost Benchmark

RPP 93.6

With an RPP of 93.6, South Carolina is within a few percent of the national cost-of-living baseline. Salary adjustment for Nurse Practitioners is therefore minor — what you earn is close to what you'd keep in real purchasing power.

Meaningful Purchasing-Power Shift

+6.8%

After applying South Carolina's RPP, the $123,290 median salary translates to $131,720 in real terms — a 6.8% gain. That difference can cover several months of expenses over a year for a Nurse Practitioners.

Below-Median Adjusted Pay

#37 / 51

South Carolina's rank of #37 of 51 states means real purchasing power for Nurse Practitioners trails the national half-way line.

Best States for Nurse Practitioners (After Cost of Living)

Where does Nurse Practitioners salary stretch the furthest? Top 10 states ranked by COL-adjusted median salary.

1. Alaska
$152,127
RPP 102.0
2. Montana
$151,949
RPP 90.3
$151,120
RPP 91.0
$150,213
RPP 88.8
$149,795
RPP 112.5
6. Iowa
$147,239
RPP 88.4
$147,138
RPP 89.8
$146,640
RPP 88.7
$146,424
RPP 108.8
$146,409
RPP 88.0

South Carolina ranks #37 out of 51 states for Nurse Practitioners after cost-of-living adjustment.

How much do you actually take home? See Nurse Practitioners take-home pay in South Carolina after taxes →

Frequently Asked Questions

What is the real salary for a Nurse Practitioners in South Carolina after cost of living?

A Nurse Practitioners in South Carolina earns a median salary of $123,290 per year. After adjusting for South Carolina's cost of living (RPP=93.6), the real purchasing power is $131,720 — a +6.8% difference.

Is South Carolina expensive to live in?

South Carolina's cost of living is 6.4% lower than the national average according to the BEA Regional Price Parities (2022). The RPP index for South Carolina is 93.6 (US average = 100).

What are Regional Price Parities (RPP)?

Regional Price Parities (RPPs) are price indexes published by the U.S. Bureau of Economic Analysis (BEA) that measure differences in price levels across states. They are expressed as a percentage of the national average (US = 100). Higher RPP means higher cost of living.

How is the cost-of-living adjusted salary calculated?

The adjusted salary is calculated as: Nominal Salary x (100 / RPP). For a Nurse Practitioners in South Carolina: $123,290 x (100 / 93.6) = $131,720. This represents what the salary would be worth in a state with average living costs.

Is it better to be a Nurse Practitioners in South Carolina financially?

From a purchasing power perspective, yes. A Nurse Practitioners in South Carolina enjoys 6.8% more buying power than the nominal salary suggests, because living costs are below the national average. However, other factors like job availability, career growth, and quality of life also matter.

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