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Physician Assistants Salary in Missouri: Cost of Living Adjusted (2025)

Last updated: 2025 BLS data · Page refreshed:

What does a Physician Assistants salary really buy you in Missouri?

Missouri is 8.9% cheaper than the US average

Data: BLS OEWS 2025 + BEA Regional Price Parities 2022 • Updated 2026-05-19

Nominal Salary
$135,130
Median annual (2025)
+9.8%
Real Purchasing Power
$148,331
COL-adjusted (RPP=91.1)

Missouri Cost of Living Index

Missouri's Regional Price Parity (RPP) is 91.1, meaning prices are 8.9% lower the national average. A Physician Assistants earning $135,130 in Missouri has the equivalent purchasing power of $148,331 in an average-cost US state.

MO: 91.1
Cheapest (~85) US Avg (100) Priciest (~115)

Salary Breakdown: Nominal vs. COL-Adjusted

Every dollar goes further in low-cost states. Here is how each salary percentile compares after adjusting for Missouri's cost of living.

Percentile Nominal Salary COL-Adjusted Difference
10th Percentile (P10) $82,690 $90,768 +$8,078
25th Percentile (P25) $121,680 $133,567 +$11,887
Median (P50) $135,130 $148,331 +$13,201
75th Percentile (P75) $163,170 $179,110 +$15,940
90th Percentile (P90) $169,650 $186,223 +$16,573
Key Insight

A Physician Assistants in Missouri earns $135,130 on paper, but low living costs mean your money goes 10% further — like earning $148,331 in an average-cost state. This makes Missouri one of the best value states for this occupation.

What the Cost-of-Living Data Says

Missouri Runs Well Below National Cost

RPP 91.1

Missouri's Regional Price Parity (RPP) of 91.1 means a basket of goods and services costs about 8.9% less than the national average. For a Physician Assistants, every dollar earned effectively buys more here than in a 100-RPP state.

Meaningful Purchasing-Power Shift

+9.8%

After applying Missouri's RPP, the $135,130 median salary translates to $148,332 in real terms — a 9.8% gain. That difference can cover several months of expenses over a year for a Physician Assistants.

Top-Quartile Adjusted Earnings in Missouri

#11 / 51

Ranked on COL-adjusted median pay for Physician Assistants, Missouri places #11 of 51 states — top quartile. Either nominal wages run high, cost of living runs low, or both.

Best States for Physician Assistants (After Cost of Living)

Where does Physician Assistants salary stretch the furthest? Top 10 states ranked by COL-adjusted median salary.

1. Montana
$156,666
RPP 90.3
$153,772
RPP 88.8
$153,758
RPP 91.0
4. Iowa
$152,454
RPP 88.4
$152,288
RPP 108.8
$151,363
RPP 88.0
$150,450
RPP 88.7
$149,690
RPP 109.8
$149,516
RPP 107.6
10. Vermont
$148,852
RPP 101.1

Missouri ranks #11 out of 51 states for Physician Assistants after cost-of-living adjustment.

How much do you actually take home? See Physician Assistants take-home pay in Missouri after taxes →

Frequently Asked Questions

What is the real salary for a Physician Assistants in Missouri after cost of living?

A Physician Assistants in Missouri earns a median salary of $135,130 per year. After adjusting for Missouri's cost of living (RPP=91.1), the real purchasing power is $148,331 — a +9.8% difference.

Is Missouri expensive to live in?

Missouri's cost of living is 8.9% lower than the national average according to the BEA Regional Price Parities (2022). The RPP index for Missouri is 91.1 (US average = 100).

What are Regional Price Parities (RPP)?

Regional Price Parities (RPPs) are price indexes published by the U.S. Bureau of Economic Analysis (BEA) that measure differences in price levels across states. They are expressed as a percentage of the national average (US = 100). Higher RPP means higher cost of living.

How is the cost-of-living adjusted salary calculated?

The adjusted salary is calculated as: Nominal Salary x (100 / RPP). For a Physician Assistants in Missouri: $135,130 x (100 / 91.1) = $148,331. This represents what the salary would be worth in a state with average living costs.

Is it better to be a Physician Assistants in Missouri financially?

From a purchasing power perspective, yes. A Physician Assistants in Missouri enjoys 9.8% more buying power than the nominal salary suggests, because living costs are below the national average. However, other factors like job availability, career growth, and quality of life also matter.

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