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Nurse Practitioners Salary in Missouri

Last updated: 2025 BLS data · Page refreshed:

How much do Nurse Practitioners make in Missouri?

Last updated: 2025 data from the Bureau of Labor Statistics

$129,930
Median Annual Salary
▲ +2.8% vs 2024
$130,970
Mean Salary
$129,930
Median Salary
$62.47
Hourly Rate
7,710 people work as Nurse Practitioners in Missouri

Nurse Practitioners salary by percentile in Missouri

BLS-reported salary distribution — from entry-level (10th percentile) to top earners (90th percentile).

Nurse Practitioners salary in Missouri — 2025 BLS percentilesHorizontal bars showing 10th, 25th, 50th, 75th and 90th percentile annual salaries for Nurse Practitioners in Missouri.10thBottom 10% earn less than $100,650$100,65025th25% earn less than $119,910$119,910MedianHalf earn more than $129,930$129,93075th75% earn less than $144,640$144,64090thTop 10% earn more than $162,060$162,060

Nurse Practitioners in Missouri earn a median salary of $129,930 per year ($10,827/month). This is 2.9% below the national average of $133,771. Missouri ranks #35 out of 51 states for Nurse Practitioners pay. Approximately 7,710 people work in this occupation across Missouri. Salaries increased by 2.8% compared to 2024.

About This Job: Nurse Practitioners

Diagnose and treat acute, episodic, or chronic illness, independently or as part of a healthcare team. May focus on health promotion and disease prevention. May order, perform, or interpret diagnostic tests such as lab work and x rays. May prescribe medication. Must be registered nurses who have specialized graduate education.

Top Skills

Reading Comprehension
4.12
Active Listening
4.12
Critical Thinking
4.12
Complex Problem Solving
4.12
Writing
4.0

Key Knowledge Areas

Medicine and Dentistry
4.83
English Language
4.26
Biology
4.22
Psychology
4.17
Customer and Personal Service
4.13
Typical Education: Master's Degree (65.2% of workers)

Source: O*NET OnLine, U.S. Department of Labor

Salary Range: Nurse Practitioners in Missouri

Salaries for Nurse Practitioners in Missouri range from $100,650 at the 10th percentile (entry level) to $162,060 at the 90th percentile (experienced). The middle 50% earn between $119,910 and $144,640.

Median $129,930
P10: $100,650 P25: $119,910 P75: $144,640 P90: $162,060
10th
$100,650
25th
$119,910
Median
$129,930
75th
$144,640
90th
$162,060
Percentile Annual Salary Hourly Rate Monthly
10th Percentile (Entry Level) $100,650 $48.39 $8,387
25th Percentile $119,910 $57.65 $9,992
Median (50th) $129,930 $62.47 $10,827
75th Percentile $144,640 $69.54 $12,053
90th Percentile (Experienced) $162,060 $77.91 $13,505

Note: The mean (average) salary of $130,970 differs from the median because salary distributions are typically skewed by high earners.

📊 How Does This Compare?

#35
Missouri ranks #35 of 51 states
$133,771
National avg. for Nurse Practitioners
-2.9%
vs. national average
Near Average

What does this salary really buy? See Nurse Practitioners salary in Missouri adjusted for cost of living →

How much do you actually take home? See Nurse Practitioners take-home pay in Missouri after taxes →

Explore Nurse Practitioners Data in Missouri

Nurse Practitioners Salary by State

Compare Nurse Practitioners pay across states — sorted by highest median salary.

View all 50 states →

Frequently Asked Questions

How much do Nurse Practitioners make in Missouri?
The median annual salary for Nurse Practitioners in Missouri is $129,930 as of 2025. The average (mean) salary is $130,970.
What is the salary range for a Nurse Practitioners in Missouri?
Salaries for Nurse Practitioners in Missouri range from $100,650 at the 10th percentile to $162,060 at the 90th percentile. The middle 50% earn between $119,910 and $144,640.
What is the starting salary for a Nurse Practitioners in Missouri?
Entry-level Nurse Practitioners positions in Missouri typically start around $100,650 (10th percentile). With some experience, salaries rise to $119,910 (25th percentile).
How many people work as Nurse Practitioners in Missouri?
According to 2025 BLS data, approximately 7,710 people are employed as Nurse Practitioners in Missouri.
What is the hourly rate for a Nurse Practitioners in Missouri?
Based on a standard 2,080-hour work year, the median hourly rate for a Nurse Practitioners in Missouri is approximately $62.47 per hour.

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Data Source & Methodology

Salary data is sourced from the U.S. Bureau of Labor Statistics (BLS) Occupational Employment and Wage Statistics (OEWS) survey, 2025 estimates. The OEWS survey covers approximately 1.1 million establishments nationwide.

Annual salaries are calculated based on a standard 2,080-hour work year. Actual compensation may vary based on experience, education, employer, and local market conditions. Figures do not include benefits, bonuses, or overtime pay.

Our Methodology · Data Sources · Source: BLS OEWS

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